While staying in the building, however, Jules learns that other people, predominantly apartment sitters, have gone missing in The Bartholomew. For Jules, this job is an opportunity to start over and live out a childhood fantasy. Jules's parents committed suicide by setting their home on fire shortly after Jane's disappearance. Jules's sister, Jane, also loved the book, but went missing years ago. Jules has always dreamed of living in The Bartholomew since her favorite book is 'The Heart of a Dreamer' written by Greta Manville. She explains that they cannot let an apartment sit empty for more than a month's time, so as to deter burglars, and that Jules will live in the apartment until the family determines what they want to do with the unit. Leslie Evelyn is the woman in charge of hiring new tenants. With no job prospects, Jules answers a job posting for an apartment sitter for an upscale apartment in The Bartholomew after the death of its occupant.

She lost both her job and her boyfriend, Andrew, and is now living with her best friend, Chloe, in New York City.

This synopsis is in chronological order as opposed to book order. The novel is set primarily during Jules's time in the apartment building and is interspersed with portions set during current day, when Jules has attempted to flee the building for reasons that become apparent as the plot progresses. The novel made the New York Times Bestseller List for July 21, 2019. Lock Every Door is a 2019 thriller novel by American author Todd Ritter, writing under the pen name of Riley Sager.

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